Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.36 |
| ▸ | PTP4A3 | O75365 | 4/20 | 0.36 |
| ▸ | PPIA | P62937 | 1/20 | 0.36 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4132551 | 0.85 | PTP4A3 (0.37) | EGFRPTP4A3PPIACISD1POLB | |
| SCHEMBL4132553 | 0.85 | PTP4A3 (0.37) | EGFRPTP4A3PPIACISD1POLB | |
| SCHEMBL4134460 | 0.83 | PTP4A3 (0.36) | EGFRPTP4A3PPIACISD1POLB | |
| SCHEMBL4134464 | 0.83 | PTP4A3 (0.36) | EGFRPTP4A3PPIACISD1POLB | |
| SCHEMBL4137639 | 0.79 | PTP4A3 (0.51) | PTP4A3CISD1PPARGPOLBPTPN1 | |
| SCHEMBL4137638 | 0.79 | PTP4A3 (0.51) | PTP4A3CISD1PPARGPOLBPTPN1 | |
| SCHEMBL4133914 | 0.77 | EGFR (0.39) | EGFRPPIAMEN1KMT2APTPN1 | |
| SCHEMBL4133912 | 0.77 | EGFR (0.39) | EGFRPPIAMEN1KMT2APTPN1 | |
| SCHEMBL4131686 | 0.76 | MEN1 (0.45) | PTP4A3CISD1PPARGPOLBMEN1 | |
| SCHEMBL4131690 | 0.76 | MEN1 (0.45) | PTP4A3CISD1PPARGPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934192-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | Torrent Pharmaceuticals Ltd (IN) | 2008-06-25 | — | — | EP | claimed |
| WO-2007032028-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | TORRENT PHARMACEUTICALS LTD. (IN) | 2007-03-22 | — | — | WO | claimed |