Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 4/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 14/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634780 | 1.00 | PTGER3 (0.37) | PTGER3HDAC4HDAC8PPARGALOX5 | |
| SCHEMBL4133218 | 0.81 | PTGER3 (0.37) | PTGER3HDAC4HDAC8PPARGPTGER1 | |
| SCHEMBL4122909 | 0.75 | HDAC4 (0.41) | HDAC4HDAC8PPARGALOX5 | |
| SCHEMBL4122907 | 0.75 | HDAC4 (0.41) | HDAC4HDAC8PPARGALOX5 | |
| SCHEMBL4137727 | 0.75 | EGFR (0.54) | HDAC4HDAC8PPARGALOX5 | |
| SCHEMBL4134117 | 0.74 | PTPN22 (0.51) | HDAC4HDAC8PPARGALOX5 | |
| SCHEMBL4134114 | 0.74 | PTPN22 (0.51) | HDAC4HDAC8PPARGALOX5 | |
| SCHEMBL4137723 | 0.74 | EGFR (0.53) | HDAC4HDAC8PPARGALOX5 | |
| SCHEMBL4137726 | 0.74 | EGFR (0.53) | HDAC4HDAC8PPARGALOX5 | |
| SCHEMBL4133908 | 0.74 | EGFR (0.55) | HDAC4ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934192-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | Torrent Pharmaceuticals Ltd (IN) | 2008-06-25 | — | — | EP | claimed |
| WO-2007032028-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | TORRENT PHARMACEUTICALS LTD. (IN) | 2007-03-22 | — | — | WO | claimed |