Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4136975 | 0.93 | MEN1 (0.33) | KMT2ATDP1MEN1MAPTALDH1A1 | |
| SCHEMBL4136968 | 0.93 | MEN1 (0.33) | KMT2ATDP1MEN1MAPTALDH1A1 | |
| SCHEMBL4120885 | 0.74 | HPGD (0.34) | KMT2ATDP1MEN1HPGD | |
| SCHEMBL4120886 | 0.74 | HPGD (0.34) | KMT2ATDP1MEN1HPGD | |
| SCHEMBL4138228 | 0.73 | TDP1 (0.32) | KMT2ATDP1MEN1MAPTALDH1A1 | |
| SCHEMBL4138226 | 0.73 | TDP1 (0.32) | KMT2ATDP1MEN1MAPTALDH1A1 | |
| SCHEMBL4134027 | 0.71 | CHEK1 (0.32) | KMT2ATDP1MEN1HPGD | |
| SCHEMBL4634371 | 0.69 | TDP1 (0.35) | KMT2ATDP1MEN1MAPTALDH1A1 | |
| Acetic Acid SCHEMBL4137467 | 0.68 | MEN1 (0.38) | KMT2ATDP1MEN1MAPTALDH1A1 | |
| Acetic Acid SCHEMBL4137474 | 0.68 | MEN1 (0.38) | KMT2ATDP1MEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934192-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | Torrent Pharmaceuticals Ltd (IN) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007032028-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | TORRENT PHARMACEUTICALS LTD. (IN) | 2007-03-22 | — | — | WO | disclosed |