Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTP4A3 | O75365 | 6/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL4125635 | 0.95 | PTP4A3 (0.48) | PTP4A3PTPN1MEN1KMT2AALDH1A1 | |
| Acetic Acid SCHEMBL4125639 | 0.95 | PTP4A3 (0.48) | PTP4A3PTPN1MEN1KMT2AALDH1A1 | |
| Propionic Acid SCHEMBL4133739 | 0.94 | PTP4A3 (0.47) | PTP4A3PTPN1MEN1KMT2AALDH1A1 | |
| Butyric Acid SCHEMBL4635070 | 0.92 | PTP4A3 (0.45) | PTP4A3PTPN1MEN1KMT2AALDH1A1 | |
| Acetic Acid SCHEMBL4129247 | 0.91 | PTP4A3 (0.44) | PTP4A3PTPN1MEN1KMT2AALDH1A1 | |
| Acetic Acid SCHEMBL4129246 | 0.91 | PTP4A3 (0.44) | PTP4A3PTPN1MEN1KMT2AALDH1A1 | |
| Acetic Acid SCHEMBL4132602 | 0.90 | PTP4A3 (0.43) | PTP4A3MEN1KMT2AALDH1A1KDM4E | |
| Acetic Acid SCHEMBL4635122 | 0.90 | TDP1 (0.44) | PTP4A3PTPN1MEN1KMT2AALDH1A1 | |
| Acetic Acid SCHEMBL4132607 | 0.90 | PTP4A3 (0.43) | PTP4A3MEN1KMT2AALDH1A1KDM4E | |
| Acetic Acid SCHEMBL4635119 | 0.90 | TDP1 (0.44) | PTP4A3PTPN1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934192-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | Torrent Pharmaceuticals Ltd (IN) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007032028-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | TORRENT PHARMACEUTICALS LTD. (IN) | 2007-03-22 | — | — | WO | disclosed |