Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | FAP | Q12884 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3969423 | 0.99 | DPP4 (0.66) | DPP4ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL4636235 | 0.92 | DPP4 (0.61) | DPP4ALDH1A1LMNAMAPTTSHR | |
| Hydrochloric Acid SCHEMBL3967438 | 0.91 | DPP4 (0.60) | DPP4ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL3968701 | 0.91 | DPP4 (0.65) | DPP4ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL4634966 | 0.90 | DPP4 (0.59) | DPP4ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL3972014 | 0.90 | DPP4 (0.64) | DPP4ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL3971432 | 0.89 | DPP4 (0.73) | DPP4ALDH1A1LMNAMAPTTSHR | |
| Hydrochloric Acid SCHEMBL3971423 | 0.89 | DPP4 (0.58) | DPP4ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL3964227 | 0.88 | DPP4 (0.72) | DPP4ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL3971958 | 0.87 | DPP4 (0.71) | DPP4ALDH1A1LMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532150-B1 | NOVEL PURINE DERIVATIVES, PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-06-11 | — | — | EP | disclosed |
| EP-1532150-A1 | NOVEL PURINE DERIVATIVES, PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004018469-A1 | NOVEL PURINE DERIVATIVES, PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-03-04 | — | — | WO | disclosed |