SCHEMBL4635536

SCHEMBL4635536

Cc1ccc(CCC=CC=CCCc2cccc(C)c2)cc1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.50
GPR52 Q9Y2T5 3/20 0.49
IDO1 P14902 2/20 0.44
HRH3 Q9Y5N1 3/20 0.42
GPR84 Q9NQS5 1/20 0.40
KCNH2 Q12809 1/20 0.40
DAO P14920 2/20 0.39
IGF1R P08069 1/20 0.39
ALOX15 P16050 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2A6 P11509 1/20 0.38
RAB9A P51151 1/20 0.37
ACHE P22303 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9010941 0.88 TAAR1 (0.49) TAAR1GPR52IDO1HRH3GPR84
SCHEMBL4953940 0.83 TAAR1 (0.63) TAAR1IDO1HRH3GPR84KCNH2
SCHEMBL9011193 0.80 TAAR1 (0.55) TAAR1GPR52IDO1HRH3GPR84
SCHEMBL4431762 0.80 TAAR1 (0.55) TAAR1GPR52IDO1HRH3GPR84
SCHEMBL4431759 0.80 TAAR1 (0.55) TAAR1GPR52IDO1HRH3GPR84
SCHEMBL9163168 0.79 TAAR1 (0.50) TAAR1GPR52IDO1HRH3GPR84
SCHEMBL1082483 0.79 TAAR1 (0.53) TAAR1GPR52IDO1HRH3GPR84
SCHEMBL106719 0.79 TAAR1 (0.53) TAAR1GPR52IDO1HRH3GPR84
SCHEMBL28686625 0.79 TAAR1 (0.53) TAAR1GPR52IDO1HRH3GPR84
SCHEMBL18556638 0.78 TAAR1 (0.57) TAAR1IDO1HRH3GPR84KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1934418-A1 UTILITY POLE OF THERMOPLASTIC COMPOSITE MATERIAL Pirelli & C. S.p.A. (IT) 2008-06-25 EP disclosed
WO-2007042058-A1 UTILITY POLE OF THERMOPLASTIC COMPOSITE MATERIAL PIRELLI & C. S.P.A. (IT) 2007-04-19 WO disclosed