Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 1.00 |
| ▸ | DPP8 | Q6V1X1 | 16/20 | 1.00 |
| ▸ | DPP9 | Q86TI2 | 16/20 | 1.00 |
| ▸ | DPP7 | Q9UHL4 | 15/20 | 1.00 |
| ▸ | PREP | P48147 | 11/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4897275 | 1.00 | DPP4 (1.00) | DPP4DPP8DPP9DPP7PREP | |
| SCHEMBL4892891 | 0.87 | DPP4 (1.00) | DPP4DPP8DPP9DPP7PREP | |
| SCHEMBL4897238 | 0.86 | DPP4 (1.00) | DPP4DPP8DPP9DPP7PREP | |
| SCHEMBL5215233 | 0.86 | DPP4 (0.77) | DPP4DPP8DPP9DPP7PREP | |
| SCHEMBL6610538 | 0.86 | DPP4 (0.77) | DPP4DPP8DPP9DPP7PREP | |
| Hydrochloric Acid SCHEMBL5222097 | 0.85 | DPP4 (0.75) | DPP4DPP8DPP9DPP7PREP | |
| SCHEMBL4636508 | 0.82 | DPP4 (1.00) | DPP4DPP8DPP9DPP7PREP | |
| SCHEMBL4894724 | 0.82 | DPP4 (1.00) | DPP4DPP8DPP9DPP7PREP | |
| SCHEMBL4896836 | 0.82 | DPP4 (1.00) | DPP4DPP8DPP9DPP7PREP | |
| SCHEMBL4898094 | 0.82 | DPP4 (1.00) | DPP4DPP8DPP9DPP7PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931633-A2 | DERIVATIVES OF 3-AZABICYCLO[3.1.0]HEXANE AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007029086-A2 | DERIVATIVES OF 3-AZABICYCLO[3.1.0]HEXANE AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |