Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 14/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 12/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2690240 | 0.82 | SLC6A4 (0.66) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL2691930 | 0.82 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL2690100 | 0.80 | SLC6A2 (0.71) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL2689223 | 0.77 | SLC6A4 (0.71) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL2689785 | 0.77 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL14946771 | 0.77 | SLC6A4 (0.77) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL2690476 | 0.77 | SLC6A4 (0.81) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL2691516 | 0.75 | SLC6A4 (0.68) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL2698801 | 0.74 | SLC6A4 (0.67) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL2689350 | 0.74 | SLC6A4 (0.66) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771435-A4 | MODULATORS OF CENTRAL NERVOUS SYSTEM NEUROTRANSMITTERS | HUMAN BIOMOLECULAR RES INST (US) | 2008-02-13 | — | — | EP | disclosed |
| EP-1771435-A2 | MODULATORS OF CENTRAL NERVOUS SYSTEM NEUROTRANSMITTERS | Human Biomolecular Research Institute (US) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006025920-A2 | MODULATORS OF CENTRAL NERVOUS SYSTEM NEUROTRANSMITTERS | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2006-03-09 | — | — | WO | disclosed |