Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 6/20 | 0.48 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.48 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.48 |
| ▸ | MTOR | P42345 | 2/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.48 |
| ▸ | CLK1 | P49759 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.48 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.48 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.48 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.48 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4636794 | 1.00 | PIM1 (0.48) | PIM1PIM2DYRK1APIK3CDCSNK2A2 | |
| SCHEMBL2877560 | 0.92 | CISD1 (0.56) | PIM1PIM2DYRK1APIK3CDCSNK2A2 | |
| SCHEMBL12975471 | 0.92 | CISD1 (0.56) | PIM1PIM2DYRK1APIK3CDCSNK2A2 | |
| SCHEMBL2877564 | 0.92 | CISD1 (0.56) | PIM1PIM2DYRK1APIK3CDCSNK2A2 | |
| SCHEMBL2882652 | 0.92 | PIM1 (0.56) | PIM1PIM2DYRK1APIK3CDCSNK2A2 | |
| SCHEMBL12975474 | 0.92 | PIM1 (0.56) | PIM1PIM2DYRK1APIK3CDCSNK2A2 | |
| SCHEMBL2882650 | 0.92 | PIM1 (0.56) | PIM1PIM2DYRK1APIK3CDCSNK2A2 | |
| SCHEMBL12975478 | 0.82 | MEN1 (0.50) | PIM1DYRK1APIK3CDCSNK2A2PIK3CA | |
| SCHEMBL2882464 | 0.82 | MEN1 (0.50) | PIM1DYRK1APIK3CDCSNK2A2PIK3CA | |
| SCHEMBL2882465 | 0.82 | MEN1 (0.50) | PIM1DYRK1APIK3CDCSNK2A2PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931424-A2 | P13K INHIBITORS FOR THE TREATMENT OF ENDOMETRIOSIS | LABORATOIRES SERONO S.A. (CH) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007030360-A2 | P13K INHIBITORS FOR THE TREATMENT OF ENDOMETRIOSIS | LABORATOIRES SERONO S.A. (CH) | 2007-03-15 | — | — | WO | disclosed |