Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 0.66 |
| ▸ | PPARG | P37231 | 15/20 | 0.66 |
| ▸ | PPARA | Q07869 | 6/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL334711 | 0.88 | PPARD (0.85) | PPARDPPARGPPARACYP2C9CYP3A4 | |
| SCHEMBL10219908 | 0.82 | PPARD (0.60) | PPARDPPARGPPARACYP2C9 | |
| SCHEMBL334847 | 0.81 | PPARD (0.60) | PPARDPPARGPPARACYP2C9 | |
| SCHEMBL10220994 | 0.80 | PPARD (0.85) | PPARDPPARGPPARACYP2C9CYP3A4 | |
| SCHEMBL4637591 | 0.80 | PPARD (0.59) | PPARDPPARGPPARACYP2C9CYP3A4 | |
| SCHEMBL334547 | 0.80 | PPARD (1.00) | PPARDPPARGPPARACYP2C9CYP3A4 | |
| SCHEMBL10221068 | 0.79 | PPARD (0.84) | PPARDPPARGPPARACYP2C9CYP3A4 | |
| SCHEMBL333917 | 0.79 | PPARD (0.62) | PPARDPPARGPPARACYP2C9 | |
| SCHEMBL10219891 | 0.79 | PPARD (0.64) | PPARDPPARGPPARACYP2C9 | |
| SCHEMBL334394 | 0.79 | PPARD (0.59) | PPARDPPARGPPARACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1939189-A1 | DERIVATIVE HAVING PPAR AGONISTIC ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2008-07-02 | — | — | EP | disclosed |