Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.65 |
| ▸ | TSHR | P16473 | 6/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.65 |
| ▸ | RECQL | P46063 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | THRB | P10828 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29392695 | 0.91 | TTR (0.82) | TTRHSD17B10TSHRCYP3A4RECQL | |
| Propane SCHEMBL29003929 | 0.88 | TTR (0.78) | TTRHSD17B10TSHRCYP3A4RECQL | |
| SCHEMBL8578252 | 0.84 | TTR (0.70) | TTRHSD17B10TSHRCYP3A4RECQL | |
| SCHEMBL3564211 | 0.84 | TTR (0.70) | TTRHSD17B10TSHRCYP3A4RECQL | |
| SCHEMBL3566720 | 0.84 | TTR (0.70) | TTRHSD17B10TSHRCYP3A4RECQL | |
| SCHEMBL8773713 | 0.84 | AHR (0.70) | TTRHSD17B10TSHRCYP3A4RECQL | |
| SCHEMBL11788820 | 0.84 | TTR (0.70) | TTRHSD17B10TSHRCYP3A4RECQL | |
| SCHEMBL9579791 | 0.80 | TTR (0.64) | TTRHSD17B10TSHRCYP3A4RECQL | |
| SCHEMBL2806380 | 0.80 | TTR (0.65) | TTRHSD17B10TSHRCYP3A4RECQL | |
| SCHEMBL2574718 | 0.79 | HSD17B10 (0.65) | TTRHSD17B10TSHRCYP3A4RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0379058-B1 | Vinyl ester resins containing mesogenic/rigid rodlike moieties | DOW CHEMICAL CO (US) | 1999-09-29 | — | — | EP | claimed |
| US-5342904-A | Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties | THE DOW CHEMICAL COMPANY (US) | 1994-08-30 | — | — | US | claimed |
| US-5248740-A | Thioepoxides, liquid crystal polymers | THE DOW CHEMICAL COMPANY (US) | 1993-09-28 | — | — | US | claimed |
| US-5235008-A | Curable | THE DOW CHEMICAL COMPANY (US) | 1993-08-10 | — | — | US | claimed |
| US-5164464-A | Liquid crystalline polymers, acrylated epoxy resins | THE DOW CHEMICAL COMPANY (US) | 1992-11-17 | — | — | US | claimed |
| US-4962163-A | ADVANCED POLYEPOXIDES AND EPOXY RESINS MODIFIED BY AN UNSATURATED CARBOXYLIC ACID; CURED COATING AND FILMS HAVINGI IMPROVED TENSILE AND FLEXURAL STRENGTH AND MODULUS | THE DOW CHEMICAL COMPANY (US) | 1990-10-09 | — | — | US | claimed |
| EP-0379058-A2 | Vinyl ester resins containing mesogenic/rigid rodlike moieties | THE DOW CHEMICAL COMPANY (US) | 1990-07-25 | — | — | EP | claimed |
| US-20240226160-A9 | ACTIVITY-INDUCIBLE FUSION PROTEINS HAVING A HEAT SHOCK PROTEIN 90 BINDING DOMAIN | SEATTLE CHILDREN'S HOSPITAL D/B/A SEATTLE CHILDREN'S RESEARCH INSTITUTE (US) | 2024-07-11 | — | — | US | disclosed |
| US-20240131072-A1 | ACTIVITY-INDUCIBLE FUSION PROTEINS HAVING A HEAT SHOCK PROTEIN 90 BINDING DOMAIN | SEATTLE CHILDREN'S HOSPITAL D/B/A SEATTLE CHILDREN'S RESEARCH INSTITUTE (US) | 2024-04-25 | — | — | US | disclosed |
| EP-4291571-A2 | ACTIVITY-INDUCIBLE FUSION PROTEINS HAVING A HEAT SHOCK PROTEIN 90 BINDING DOMAIN | Seattle Children's Hospital d/b/a Seattle Children's Research Institute (US) | 2023-12-20 | — | — | EP | disclosed |
| US-20230322925-A1 | PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS | SEATTLE CHILDREN’S HOSPITAL DBA SEATTLE CHILDREN’S RES INSTITUTE (US) | 2023-10-12 | — | — | US | disclosed |
| EP-3681504-B1 | METHODS OF DETECTION USING X-RAY FLUORESCENCE | ICAGEN INC (US) | 2023-08-23 | — | — | EP | disclosed |
| US-20230172981-A1 | METHODS AND COMPOSITIONS FOR STIMULATION OF CHIMERIC ANTIGEN RECEPTOR T CELLS WITH HAPTEN LABELLED CELLS | SEATTLE CHILDRENS HOSPITAL DBA SEATTLE CHILDRENS RES INST (US) | 2023-06-08 | — | — | US | disclosed |
| US-4487915-A | CASTINGS, COATINGS, LAMINATION | THE DOW CHEMICAL COMPANY (US) | 1984-12-11 | — | — | US | disclosed |
| US-4345051-A | Block copolymers of polyphenylene oxides and polyformals of sterically-hindered dihydric phenols | GENERAL ELECTRIC COMPANY (US) | 1982-08-17 | — | — | US | disclosed |
| US-4126602-A | THERMOPLASTIC, MOLDING, HYDROLYTIC STABILITY | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1978-11-21 | — | — | US | disclosed |
| US-4096341-A | MONOMERS FOR POLYESTERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-06-20 | — | — | US | disclosed |
| US-4085091-A | Thermally stable, rigid polyesters from thermally stable, rigid dibasic acids and aromatic dihydroxy compounds | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1978-04-18 | — | — | US | disclosed |
| US-4026827-A | Preparation of high-molecular weight thermoplastic polyorganosilicic acid esters | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) | 1977-05-31 | — | — | US | disclosed |
| US-3991014-A | Polyesters of derivatives of hydroquinone and bis(carboxyphenyl)ether | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322925-A1 | PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS | PHOSPHO1, LCAT, CD47 | TTR 764/4885HSD17B10 2818/4885TSHR 1224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.