SCHEMBL4638470

SCHEMBL4638470

CCOC(=O)C(C)N([C@H]1CCN(c2ccc3c(c2)CCCN(C(=O)O)C3C(C)(C)C)C1=O)S(=O)(=O)/C=C/c1ccc(Cl)s1

nearest known ligand 0.44

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4638475 0.90 F10 (0.44) F10
SCHEMBL4932068 0.83 F10 (0.43) F10
SCHEMBL4932059 0.83 F10 (0.43) F10
SCHEMBL5242415 0.82 F10 (0.52) F10
SCHEMBL4930974 0.82 F10 (0.59) F10
SCHEMBL4637512 0.82 F10 (0.59) F10
SCHEMBL4930967 0.82 F10 (0.59) F10
Hydrochloric Acid SCHEMBL4930997 0.82 F10 (0.58) F10
Hydrochloric Acid SCHEMBL4931002 0.82 F10 (0.58) F10
Hydrochloric Acid SCHEMBL4930991 0.82 F10 (0.58) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1951712-A2 CHEMICAL COMPOUNDS GLAXO GROUP LIMITED (GB) 2008-08-06 EP disclosed
WO-2007059952-A2 1-BENZAZEPINE-3-SULFONYLAMINO-2-PYRRLORIDONES AS FACTOR XA INHIBITORS GLAXO GROUP LIMITED (GB) 2007-05-31 WO disclosed