SCHEMBL4638622

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4639730	0.90	MAOB (0.74)	MAOBHDAC1HDAC6HDAC5SPHK2
	SCHEMBL4639011	0.84	PARP10 (0.58)	MAOBHDAC1HDAC6HDAC5PARP15
	SCHEMBL4639994	0.84	MAOB (0.55)	MAOBHDAC1HDAC6HDAC5SPHK2
	SCHEMBL4638731	0.82	MAOB (0.53)	MAOBHDAC1HDAC6HDAC5PARP15
	SCHEMBL4638704	0.82	HDAC1 (0.51)	MAOBHDAC1HDAC6HDAC5PARP15
	SCHEMBL4638537	0.82	NR4A2 (0.60)	MAOBMAOAPARP15PARP14PARP10
	SCHEMBL4638181	0.82	PARP1 (0.50)	MAOBPARP15PARP14PARP10NR4A2
	SCHEMBL4639605	0.81	MAOB (0.50)	MAOBHDAC1HDAC6HDAC5PARP15
	SCHEMBL4638452	0.80	PARP10 (0.72)	MAOBHDAC1HDAC6HDAC5SPHK2
	SCHEMBL29873406	0.80	PARP10 (0.72)	MAOBHDAC1HDAC6HDAC5SPHK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.