Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 19/20 | 0.51 |
| ▸ | PPARG | P37231 | 17/20 | 0.51 |
| ▸ | PPARA | Q07869 | 12/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4637823 | 0.92 | PPARD (0.45) | PPARDPPARGPPARANPC1 | |
| SCHEMBL10220521 | 0.78 | PPARD (0.56) | PPARDPPARGPPARANPC1 | |
| SCHEMBL10220520 | 0.78 | PPARD (0.56) | PPARDPPARGPPARANPC1 | |
| SCHEMBL10221023 | 0.77 | PPARD (0.61) | PPARDPPARGPPARA | |
| SCHEMBL10220489 | 0.75 | PPARD (0.58) | PPARDPPARGPPARA | |
| SCHEMBL10220486 | 0.75 | PPARD (0.58) | PPARDPPARGPPARA | |
| SCHEMBL335796 | 0.75 | PPARD (0.61) | PPARDPPARGPPARANPC1 | |
| SCHEMBL335795 | 0.75 | PPARD (0.72) | PPARDPPARGPPARANPC1 | |
| SCHEMBL10221031 | 0.73 | PPARD (0.58) | PPARDPPARGPPARANPC1 | |
| SCHEMBL10220458 | 0.73 | PPARD (0.66) | PPARDPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1939189-A1 | DERIVATIVE HAVING PPAR AGONISTIC ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2008-07-02 | — | — | EP | disclosed |