Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 20/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2804736 | 1.00 | ADORA2A (0.42) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL14289845 | 1.00 | ADORA2A (0.42) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL2804739 | 1.00 | ADORA2A (0.42) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL2804742 | 1.00 | ADORA2A (0.42) | ADORA2AADORA3ADORA2BADORA1 | |
| Trifluoroacetic Acid SCHEMBL589844 | 0.97 | ADORA2A (0.41) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL589258 | 0.95 | ADORA2A (0.38) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL589259 | 0.95 | ADORA2A (0.38) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL589845 | 0.92 | ADORA2A (0.38) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL10156338 | 0.92 | ADORA2A (0.45) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL10155859 | 0.92 | ADORA2A (0.45) | ADORA2AADORA3ADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1889846-A1 | Purine derivatives as A2a agonists | Novartis AG (CH) | 2008-02-20 | — | — | EP | disclosed |