Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 6/20 | 0.47 |
| ▸ | PDE4A | P27815 | 6/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4279613 | 0.94 | PDE4B (0.48) | PDE4BPDE4APDE4CPDE4DHPGD | |
| SCHEMBL15429028 | 0.94 | MAPT (0.43) | PDE4BPDE4APDE4CPDE4DHPGD | |
| SCHEMBL4280362 | 0.93 | PDE4B (0.45) | PDE4BPDE4APDE4CPDE4DHPGD | |
| SCHEMBL4275646 | 0.91 | PDE4B (0.43) | PDE4BPDE4APDE4CPDE4DHPGD | |
| SCHEMBL4278639 | 0.91 | PDE4B (0.48) | PDE4BPDE4APDE4CPDE4DHPGD | |
| SCHEMBL4276037 | 0.91 | PDE4A (0.43) | PDE4BPDE4APDE4CPDE4DHPGD | |
| SCHEMBL4280788 | 0.91 | PDE4B (0.47) | PDE4BPDE4APDE4CPDE4DHPGD | |
| SCHEMBL4273841 | 0.91 | PDE4B (0.43) | PDE4BPDE4APDE4CPDE4DHPGD | |
| SCHEMBL4271668 | 0.90 | PDE4A (0.44) | PDE4BPDE4APDE4CPDE4DHPGD | |
| SCHEMBL4272488 | 0.90 | PDE4B (0.44) | PDE4BPDE4APDE4CPDE4DHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954684-A2 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | Otsuka Pharmaceutical Co., Ltd. (JP) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007058338-A2 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-05-24 | — | — | WO | disclosed |