Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 20/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4639727 | 0.90 | CETP (0.49) | CETPKCNH2 | |
| SCHEMBL4639699 | 0.88 | CETP (0.42) | CETP | |
| SCHEMBL4639333 | 0.82 | CETP (0.41) | CETPKCNH2 | |
| SCHEMBL4640342 | 0.82 | CETP (0.41) | CETP | |
| SCHEMBL4639169 | 0.81 | CETP (0.46) | CETP | |
| SCHEMBL4639790 | 0.79 | CETP (0.43) | CETP | |
| SCHEMBL1183793 | 0.78 | CETP (0.60) | CETPKCNH2 | |
| SCHEMBL1183795 | 0.78 | CETP (0.60) | CETPKCNH2 | |
| SCHEMBL27776264 | 0.78 | CETP (0.60) | CETPKCNH2 | |
| SCHEMBL4639343 | 0.74 | CETP (0.67) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951673-A2 | HETEROCYCLIC CETP INHIBITORS | Bristol-Myers Squibb Company (US) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007062314-A2 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-31 | — | — | WO | disclosed |