Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 20/20 | 0.79 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.79 |
| ▸ | SSTR1 | P30872 | 3/20 | 0.63 |
| ▸ | HRH1 | P35367 | 5/20 | 0.61 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1121612 | 0.90 | SSTR5 (0.75) | SSTR5KCNH2SSTR1HRH1HTR2B | |
| SCHEMBL1121426 | 0.88 | SSTR5 (0.77) | SSTR5KCNH2SSTR1HRH1 | |
| SCHEMBL3581959 | 0.88 | SSTR5 (1.00) | SSTR5KCNH2SSTR1HRH1HTR2B | |
| SCHEMBL1121651 | 0.88 | SSTR5 (0.77) | SSTR5KCNH2SSTR1HRH1HTR2B | |
| SCHEMBL1121278 | 0.88 | SSTR5 (0.77) | SSTR5KCNH2SSTR1HRH1HTR2B | |
| SCHEMBL1121349 | 0.88 | SSTR5 (0.79) | SSTR5KCNH2SSTR1HRH1HTR2B | |
| SCHEMBL1121475 | 0.87 | SSTR5 (0.76) | SSTR5KCNH2SSTR1HRH1HTR2B | |
| SCHEMBL4947455 | 0.87 | SSTR5 (0.80) | SSTR5KCNH2SSTR1HRH1HTR2B | |
| SCHEMBL1121352 | 0.87 | SSTR5 (0.75) | SSTR5KCNH2SSTR1HRH1 | |
| SCHEMBL4947594 | 0.86 | SSTR5 (0.80) | SSTR5KCNH2SSTR1HRH1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924579-A2 | BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007025897-A2 | BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-03-08 | — | — | WO | disclosed |