Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.59 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 3/20 | 0.57 |
| ▸ | CNR2 | P34972 | 2/20 | 0.57 |
| ▸ | NAAA | Q02083 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20490389 | 0.88 | HDAC7 (0.63) | EPHX2NPSR1HDAC7ALDH1A1HPGD | |
| SCHEMBL20490330 | 0.84 | HDAC7 (0.58) | EPHX2NPSR1HDAC7ALDH1A1HPGD | |
| SCHEMBL31119120 | 0.82 | HTT (0.69) | NPSR1HDAC7ALDH1A1HPGDHSD17B10 | |
| SCHEMBL31119121 | 0.82 | HTT (0.69) | NPSR1HDAC7ALDH1A1HPGDHSD17B10 | |
| SCHEMBL5707054 | 0.82 | HTT (0.69) | NPSR1HDAC7ALDH1A1HPGDHSD17B10 | |
| SCHEMBL5947909 | 0.81 | EPHX2 (0.64) | EPHX2NPSR1ALDH1A1HPGDMAPT | |
| Hydrochloric Acid SCHEMBL15769882 | 0.81 | HTT (0.67) | NPSR1HDAC7ALDH1A1HPGDHSD17B10 | |
| SCHEMBL8346286 | 0.81 | HTT (0.67) | NPSR1HDAC7ALDH1A1HPGDHSD17B10 | |
| SCHEMBL20490824 | 0.80 | NPSR1 (0.49) | EPHX2NPSR1HDAC7ALDH1A1HPGD | |
| SCHEMBL5948102 | 0.80 | EPHX2 (1.00) | EPHX2NPSR1ALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885697-A2 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHODS OF USING SAME | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-02-13 | — | — | EP | disclosed |
| US-20060276515-A1 | Soluble Epoxide Hydrolase Inhibitors and Methods of Using Same | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-12-07 | — | — | US | disclosed |
| WO-2006121719-A2 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHODS OF USING SAME | BOEHRINGER INGELHEIM INTERNATIONAL, GMBH (DE) | 2006-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276515-A1 | Soluble Epoxide Hydrolase Inhibitors and Methods of Using Same | EPHX1, EPHX2, NCEH1 | EPHX2 2/4885NPSR1 3713/4885HDAC7 3059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.