Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 17/20 | 0.57 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.39 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4640352 | 0.93 | CETP (0.56) | CETPKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL4639239 | 0.91 | CETP (0.59) | CETP | |
| SCHEMBL4639314 | 0.89 | CETP (0.58) | CETPKCNQ3KCNQ2KCNE1KCNQ1 | |
| SCHEMBL1182381 | 0.82 | CETP (0.82) | CETP | |
| SCHEMBL1182382 | 0.82 | CETP (0.82) | CETP | |
| SCHEMBL12871524 | 0.77 | CETP (0.74) | CETP | |
| SCHEMBL1182570 | 0.75 | CETP (0.81) | CETP | |
| SCHEMBL1182566 | 0.75 | CETP (0.81) | CETP | |
| SCHEMBL4639179 | 0.74 | CETP (0.48) | CETP | |
| SCHEMBL4639127 | 0.74 | CETP (0.53) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1951673-A2 | HETEROCYCLIC CETP INHIBITORS | Bristol-Myers Squibb Company (US) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007062314-A2 | HETEROCYCLIC CETP INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-31 | — | — | WO | disclosed |