Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4641738 | 0.92 | TRPV1 (0.48) | TRPV1 | |
| SCHEMBL4640623 | 0.90 | TRPV1 (0.51) | TRPV1 | |
| SCHEMBL5324344 | 0.90 | TRPV1 (0.48) | TRPV1 | |
| SCHEMBL5323071 | 0.89 | TRPV1 (0.49) | TRPV1 | |
| SCHEMBL4641594 | 0.88 | TRPV1 (0.54) | TRPV1 | |
| SCHEMBL4645416 | 0.87 | TRPV1 (0.47) | TRPV1 | |
| SCHEMBL5321970 | 0.87 | TRPV1 (0.52) | TRPV1 | |
| SCHEMBL5320786 | 0.87 | TRPV1 (0.52) | TRPV1 | |
| SCHEMBL5321974 | 0.87 | TRPV1 (0.52) | TRPV1 | |
| SCHEMBL4640678 | 0.86 | TRPV1 (0.52) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824837-B1 | SUBSTITUTED N-SULFONYLAMINOBENZYL-2-PHENOXY ACETAMIDE COMPOUNDS | PFIZER (US) | 2008-08-13 | — | — | EP | disclosed |
| US-7214824-B2 | Substituted N-sulfonylaminobenzyl-2-phenoxyacetamide compounds as VR1 receptor agonists | PFIZER INC. (US) | 2007-05-08 | — | — | US | disclosed |
| US-7214824-B2 | Substituted N-sulfonylaminobenzyl-2-phenoxyacetamide compounds as VR1 receptor agonists | PFIZER INC. (US) | 2007-05-08 | — | — | US | disclosed |