Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.87 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.57 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.57 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | BRD4 | O60885 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 2/20 | 0.46 |
| ▸ | ALPG | P10696 | 2/20 | 0.46 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2445116 | 0.90 | BCHE (0.74) | BCHETRPC3TRPC4TRPC5KCNH2 | |
| SCHEMBL8329416 | 0.82 | BCHE (0.66) | BCHELMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL2086623 | 0.82 | BCHE (0.62) | BCHEBRD4TSHRLMNAALDH1A1 | |
| SCHEMBL2084432 | 0.80 | BCHE (0.60) | BCHEBRD4TSHRALDH1A1 | |
| SCHEMBL13609711 | 0.80 | BCHE (0.69) | BCHELMNANPC1ALDH1A1RAB9A | |
| SCHEMBL6304380 | 0.80 | BCHE (0.69) | BCHETSHRLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL22598624 | 0.79 | BCHE (0.59) | BCHEBRD4TDP1ALDH1A1 | |
| SCHEMBL5144365 | 0.79 | BCHE (0.61) | BCHETSHRLMNAALDH1A1RAB9A | |
| SCHEMBL20232505 | 0.78 | BCHE (0.60) | BCHEBRD4ALDH1A1 | |
| SCHEMBL29642307 | 0.78 | BCHE (0.60) | BCHEBRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853084-B1 | Substituted purine derivatives as vitronectin receptor antagonists | HOECHST AG (DE) | 2008-08-13 | — | — | EP | disclosed |
| US-6723727-B1 | VITRONECTIN RECEPTOR ANTAGONISTS; INHIBITORS OF BONE RESORPTION; OSTEOPOROSIS | HOECHST AKTIENGESELLSCHAFT (DE) | 2004-04-20 | — | — | US | disclosed |
| EP-0853084-A2 | Substituted purine derivatives as vitronectin receptor antagonists | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-15 | — | — | EP | disclosed |