Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 2/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | BLM | P54132 | 3/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4736751 | 0.95 | SCN9A (0.50) | TNFSCN9AGPR84KMT2ALMNA | |
| SCHEMBL29751089 | 0.89 | TNF (0.61) | TNFSCN9AGPR84KMT2ALMNA | |
| SCHEMBL6844425 | 0.89 | TNF (0.61) | TNFSCN9AGPR84KMT2ALMNA | |
| SCHEMBL4640376 | 0.89 | TNF (0.61) | TNFSCN9AGPR84KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL29750798 | 0.88 | TNF (0.60) | TNFSCN9AGPR84KMT2ALMNA | |
| SCHEMBL31414601 | 0.78 | KMT2A (0.60) | TNFGPR84KMT2ALMNAKDM4E | |
| SCHEMBL21315702 | 0.77 | TNF (0.58) | TNFGPR84KMT2ALMNAKDM4E | |
| SCHEMBL19911037 | 0.77 | TNF (0.58) | TNFGPR84KMT2ALMNAKDM4E | |
| SCHEMBL4601569 | 0.76 | SCN9A (0.57) | SCN9AGPR84KMT2ALMNAKDM4E | |
| SCHEMBL17760581 | 0.76 | SCN9A (0.57) | SCN9AGPR84KMT2ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1956016-A1 | Bicyclic acyltryptophanols | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-08-13 | — | — | EP | disclosed |