SCHEMBL4642270

SCHEMBL4642270

[CH2]CCCC(=O)Oc1ccc(C(=O)OCC)cc1OC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B2 P37059 1/20 0.56
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
MAPT P10636 7/20 0.49
LMNA P02545 3/20 0.49
ALDH1A1 P00352 2/20 0.49
MAPK1 P28482 1/20 0.49
TSHR P16473 2/20 0.49
KMT2A Q03164 4/20 0.48
MEN1 O00255 3/20 0.48
GAA P10253 1/20 0.48
SLC22A2 O15244 1/20 0.47
TMPRSS2 O15393 1/20 0.47
F2 P00734 1/20 0.47
F10 P00742 1/20 0.47
PLG P00747 1/20 0.47
F12 P00748 1/20 0.47
PLAU P00749 1/20 0.47
PLAT P00750 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4642451 0.92 HSD17B2 (0.58) HSD17B2NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL4647751 0.89 HSD17B2 (0.57) HSD17B2NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL4645001 0.88 HSD17B2 (0.56) HSD17B2NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL4644367 0.88 HSD17B2 (0.56) HSD17B2NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL4643562 0.87 HSD17B2 (0.61) HSD17B2NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL4644621 0.86 HSD17B2 (0.54) HSD17B2NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL4644420 0.86 HSD17B2 (0.60) HSD17B2LMNAALDH1A1KMT2AMEN1
SCHEMBL4647998 0.86 HSD17B2 (0.59) HSD17B2NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL4644009 0.85 HSD17B2 (0.58) HSD17B2NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL4641813 0.83 HSD17B2 (0.62) HSD17B2NPC1RAB9ASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed