SCHEMBL4642741

SCHEMBL4642741

CCC[CH]C(=O)OC(=O)Cc1ccc(F)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.46
POLB P06746 2/20 0.46
APEX1 P27695 1/20 0.46
KMT2A Q03164 2/20 0.46
KDM4E B2RXH2 2/20 0.41
GAA P10253 2/20 0.40
MEN1 O00255 1/20 0.40
KLK7 P49862 4/20 0.40
LMNA P02545 2/20 0.40
MAPT P10636 2/20 0.40
XBP1 P17861 1/20 0.40
HIF1A Q16665 1/20 0.40
RAB9A P51151 1/20 0.40
TP53 P04637 1/20 0.39
ALOX15 P16050 1/20 0.39
MAPK1 P28482 1/20 0.39
HTT P42858 1/20 0.39
HSD17B10 Q99714 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CTBP2 P56545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4647334 0.87 KMT2A (0.48) TDP1POLBAPEX1KMT2AKDM4E
SCHEMBL4644171 0.86 POLB (0.46) POLBKMT2AKLK7MAPTRAB9A
SCHEMBL4641514 0.86 TSHR (0.47) POLBKMT2AKDM4EMEN1LMNA
SCHEMBL4644775 0.85 KMT2A (0.52) TDP1KMT2AGAAKLK7LMNA
SCHEMBL4642440 0.82 KMT2A (0.49) TDP1POLBAPEX1KMT2AKDM4E
SCHEMBL4644634 0.79 MAPT (0.45) POLBKMT2AGAAMEN1LMNA
SCHEMBL4641802 0.79 ABL1 (0.48) KMT2AGAAMEN1LMNAMAPT
SCHEMBL4642293 0.76 KMT2A (0.49) TDP1POLBAPEX1KMT2AKDM4E
SCHEMBL13481189 0.73 KLK7 (0.52) TDP1POLBAPEX1KMT2AKDM4E
SCHEMBL4644794 0.73 POLB (0.48) POLBKMT2AKLK7MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed