⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5187 | 0.95 | — | — | |
| SCHEMBL1144463 | 0.95 | — | — | |
| Fluoride SCHEMBL27727158 | 0.90 | — | — | |
| Water SCHEMBL28326999 | 0.90 | — | — | |
| SCHEMBL28111843 | 0.90 | — | — | |
| Methane SCHEMBL27978499 | 0.90 | — | — | |
| Ammonia Solution, Strong SCHEMBL2985898 | 0.89 | — | — | |
| Ammonia Solution, Strong SCHEMBL28048615 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL27279551 | 0.84 | — | — | |
| SCHEMBL8397539 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115043844-A | TRK kinase inhibitor compounds and uses thereof | 河南迈英诺医药科技有限公司 | 2022-09-13 | — | — | CN | claimed |
| WO-2023170669-A1 | CROSSLINKED POLYESTERS WITH REDUCED FLAMMABILITY | BROMINE COMPOUNDS LTD. (IL) | 2023-09-14 | — | — | WO | disclosed |
| CN-111936496-A | Use of 4- (1H-imidazol-5-yl) -1H-pyrrolo [2,3-B ] pyridine for the treatment of leukemias, lymphomas and solid tumors | 马萨里克大学 | 2020-11-13 | — | — | CN | disclosed |
| EP-1301557-B1 | COMPOSITION AND PROCESS FOR THE MANUFACTURE OF FUNCTIONALIZED POLYPHENYLENE ETHER RESINS | GEN ELECTRIC (US) | 2008-08-06 | — | — | EP | disclosed |
| US-6897282-B2 | Compositions comprising functionalized polyphenylene ether resins | GENERAL ELECTRIC (US) | 2005-05-24 | — | — | US | disclosed |
| US-6780959-B2 | BLENDS; CHEMICAL RESISTANCE, HIGH STRENGTH | GENERAL ELECTRIC COMPANY | 2004-08-24 | — | — | US | disclosed |
| US-20040102583-A1 | Compositions comprising functionalized polyphenylene ether resins | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2004-05-27 | — | — | US | disclosed |
| US-20030229196-A1 | COMPOSITIONS COMPRISING FUNCTIONALIZED POLYPHENYLENE ETHER RESINS | GENERAL ELECTRIC COMPANY (US) | 2003-12-11 | — | — | US | disclosed |
| US-6627708-B2 | Blend of polyphenylene ether (PPE) functionalized with ethenically unsaturated end groups, such as acrylated PPE with other polymers; curable systems; molded articles | GENERAL ELECTRIC COMPANY | 2003-09-30 | — | — | US | disclosed |
| EP-1301557-A1 | COMPOSITION AND PROCESS FOR THE MANUFACTURE OF FUNCTIONALIZED POLYPHENYLENE ETHER RESINS | GENERAL ELECTRIC COMPANY (US) | 2003-04-16 | — | — | EP | disclosed |
| US-6469124-B2 | ESTERIFIED AT ONE END WITH AN UNSATURATED ESTER, ESPECIALLY METHACRYLIC ACID | GENERAL ELECTRIC COMPANY | 2002-10-22 | — | — | US | disclosed |
| US-20020128400-A1 | Compositions comprising functionalized polyphenylene ether resins | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2002-09-12 | — | — | US | disclosed |
| US-20020062001-A1 | Functionalized polyphenylene ether resins and curable compositions comprising them | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2002-05-23 | — | — | US | disclosed |
| US-6384176-B1 | ENDCAPPING BY ESTERIFICATION WITH UNSATURATED CARBOXYL COMPOUND; LOW MOLECULAR WEIGHT | GENERAL ELECTRIC CO. | 2002-05-07 | — | — | US | disclosed |
| WO-2002004547-A1 | COMPOSITION AND PROCESS FOR THE MANUFACTURE OF FUNCTIONALIZED POLYPHENYLENE ETHER RESINS | GENERAL ELECTRIC COMPANY (US) | 2002-01-17 | — | — | WO | disclosed |