Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 18/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13054103 | 1.00 | MCHR1 (0.53) | MCHR1KCNH2MAPT | |
| SCHEMBL4642923 | 1.00 | MCHR1 (0.53) | MCHR1KCNH2MAPT | |
| SCHEMBL3754940 | 0.92 | MAPT (0.55) | MCHR1MAPT | |
| SCHEMBL3754936 | 0.92 | MAPT (0.55) | MCHR1MAPT | |
| SCHEMBL13054094 | 0.92 | MAPT (0.55) | MCHR1MAPT | |
| SCHEMBL3759111 | 0.92 | MCHR1 (0.46) | MCHR1KCNH2MAPT | |
| SCHEMBL13054096 | 0.92 | MCHR1 (0.46) | MCHR1KCNH2MAPT | |
| SCHEMBL3759114 | 0.92 | MCHR1 (0.46) | MCHR1KCNH2MAPT | |
| SCHEMBL13054090 | 0.92 | MAPT (0.46) | MCHR1KCNH2MAPT | |
| SCHEMBL3750062 | 0.92 | MAPT (0.47) | MCHR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828177-B1 | NOVEL MCH RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-08-13 | — | — | EP | disclosed |