SCHEMBL4644243

SCHEMBL4644243

C[CH]C(=O)Oc1ccc(C(=O)OC)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.62
CA2 P00918 2/20 0.62
MAPT P10636 4/20 0.56
KMT2A Q03164 6/20 0.54
MEN1 O00255 3/20 0.54
POLB P06746 2/20 0.54
TDP1 Q9NUW8 1/20 0.53
CA12 O43570 1/20 0.53
CA7 P43166 1/20 0.53
CA9 Q16790 1/20 0.53
CA14 Q9ULX7 1/20 0.53
ALDH1A1 P00352 2/20 0.53
ACR P10323 2/20 0.53
HGFAC Q04756 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
STS P08842 1/20 0.51
KDM4E B2RXH2 2/20 0.51
PRSS1 P07477 1/20 0.51
TSHR P16473 1/20 0.50
RAB9A P51151 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12642365 0.86 CA1 (0.64) CA1CA2MAPTKMT2AMEN1
SCHEMBL7518320 0.84 CA1 (0.72) CA1CA2MAPTKMT2AMEN1
SCHEMBL4906800 0.83 CA1 (0.60) CA1CA2MAPTKMT2AMEN1
SCHEMBL3902505 0.82 CA1 (0.69) CA1CA2MAPTKMT2AMEN1
SCHEMBL10599396 0.82 CA1 (0.69) CA1CA2MAPTKMT2AMEN1
SCHEMBL3464402 0.81 KMT2A (0.55) CA1CA2MAPTKMT2AMEN1
SCHEMBL3464400 0.81 KMT2A (0.55) CA1CA2MAPTKMT2AMEN1
SCHEMBL4641414 0.80 CA1 (0.56) CA1CA2MAPTKMT2AMEN1
SCHEMBL4642586 0.80 CA12 (0.58) CA1CA2MAPTKMT2AMEN1
SCHEMBL4647885 0.80 CA1 (0.67) CA1CA2MAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed