SCHEMBL4644269

SCHEMBL4644269

O=C(CCCl)Oc1ccccc1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.47
JAK2 O60674 1/20 0.47
LMNA P02545 1/20 0.47
MAPT P10636 1/20 0.47
KMT2A Q03164 2/20 0.42
POLB P06746 1/20 0.42
KDM4E B2RXH2 2/20 0.41
MEN1 O00255 1/20 0.41
RECQL P46063 1/20 0.41
CA1 P00915 2/20 0.41
CA12 O43570 1/20 0.41
CA7 P43166 1/20 0.41
CA14 Q9ULX7 1/20 0.41
TSHR P16473 2/20 0.41
CA2 P00918 1/20 0.41
TP53 P04637 1/20 0.41
TOP2A P11388 1/20 0.39
HPGD P15428 4/20 0.39
ALDH1A1 P00352 2/20 0.39
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4644742 0.89 GAA (0.48) GAAJAK2LMNAMAPTKMT2A
SCHEMBL688269 0.88 GAA (0.54) GAAJAK2LMNAMAPTKMT2A
SCHEMBL4644199 0.88 GAA (0.47) GAAJAK2LMNAMAPTKMT2A
SCHEMBL4644681 0.85 GAA (0.50) GAAJAK2LMNAMAPTKMT2A
SCHEMBL689958 0.85 KMT2A (0.51) GAAJAK2LMNAMAPTKMT2A
SCHEMBL688760 0.83 KMT2A (0.50) GAAJAK2LMNAMAPTKMT2A
SCHEMBL688230 0.83 KMT2A (0.50) GAAJAK2LMNAMAPTKMT2A
SCHEMBL4644726 0.83 GAA (0.48) GAAJAK2LMNAMAPTKMT2A
SCHEMBL27705570 0.81 GAA (0.47) GAAJAK2LMNAMAPTKMT2A
SCHEMBL4642501 0.81 GAA (0.47) GAAJAK2LMNAMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100519671-C Film-forming polymer and antifouling paint JOTUN AS (NO) 2009-07-29 CN disclosed
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
CN-1643085-A Film-forming polymer and antifouling paint JOTUN AS (NO) 2005-07-20 CN disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed