SCHEMBL4644285

SCHEMBL4644285

O=C(CCCCCl)C(=O)CC1CCCC1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.36
HPGD P15428 2/20 0.36
EPHX1 P07099 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.34
HDAC3 O15379 1/20 0.33
HDAC4 P56524 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC10 Q969S8 1/20 0.33
HDAC11 Q96DB2 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
HDAC9 Q9UKV0 1/20 0.33
HDAC5 Q9UQL6 1/20 0.33
CES2 O00748 4/20 0.32
CES1 P23141 4/20 0.32
KDM5A P29375 3/20 0.32
PHF8 Q9UPP1 3/20 0.32
KDM2A Q9Y2K7 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4647363 0.94 KMT2A (0.37) KMT2AHPGDEPHX1SMN1; SMN2HDAC3
SCHEMBL4643741 0.86 KMT2A (0.39) KMT2AHPGDEPHX1SMN1; SMN2EPHX2
SCHEMBL6553823 0.82 EPHX1 (0.37) KMT2AHPGDEPHX1SMN1; SMN2HDAC3
SCHEMBL28752229 0.81 KMT2A (0.36) KMT2AHPGDEPHX1SMN1; SMN2EPHX2
SCHEMBL4644513 0.80 HPGD (0.38) KMT2AHPGDEPHX1SMN1; SMN2HDAC3
SCHEMBL4642050 0.78 HPGD (0.37) KMT2AHPGDEPHX1SMN1; SMN2HDAC3
SCHEMBL4642029 0.77 EPHX1 (0.42) KMT2AHPGDEPHX1EPHX2NPC1
SCHEMBL7085369 0.76 EPHX1 (0.54) KMT2AHPGDEPHX1CES2CES1
SCHEMBL4641499 0.75 HPGD (0.41) KMT2AHPGDEPHX1SMN1; SMN2EPHX2
SCHEMBL1426277 0.72 EPHX1 (0.34) KMT2AHPGDEPHX1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed