SCHEMBL4644405

SCHEMBL4644405

CCCOC(=O)/C=C\C(=O)OC(CC)C(=O)O[Si](CCC)(CCC)CCC

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 0.46
ATM Q13315 1/20 0.41
MAPT P10636 1/20 0.36
RAB9A P51151 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
APP P05067 1/20 0.33
ALOX5 P09917 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4647146 1.00 HCAR2 (0.46) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL4644229 0.90 HCAR2 (0.45) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL4642259 0.90 HCAR2 (0.45) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL4645577 0.86 ATM (0.54) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL4641678 0.86 ATM (0.54) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL4642346 0.84 HCAR2 (0.51) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL4644098 0.84 HCAR2 (0.51) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL475818 0.81 HCAR2 (0.58) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL476040 0.81 HCAR2 (0.58) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL475820 0.81 HCAR2 (0.58) HCAR2ATMMAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed