SCHEMBL4644607

SCHEMBL4644607

COC(=O)c1ccc(OC(=O)CCCl)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.58
KMT2A Q03164 5/20 0.58
ALDH1A1 P00352 2/20 0.58
LMNA P02545 1/20 0.58
HTT P42858 1/20 0.58
HSD17B10 Q99714 1/20 0.58
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
POLB P06746 1/20 0.52
MEN1 O00255 1/20 0.49
RAB9A P51151 1/20 0.49
MGLL Q99685 1/20 0.48
ACR P10323 2/20 0.48
HGFAC Q04756 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
TDP1 Q9NUW8 1/20 0.47
CA12 O43570 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
CA14 Q9ULX7 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4641666 0.90 MAPT (0.56) MAPTKMT2AALDH1A1LMNAHTT
SCHEMBL10600742 0.90 MAPT (0.71) MAPTKMT2AALDH1A1LMNAHTT
SCHEMBL4645812 0.89 MAPT (0.54) MAPTKMT2AALDH1A1LMNAHTT
SCHEMBL4643847 0.86 CA1 (0.58) MAPTKMT2AALDH1A1LMNAHTT
SCHEMBL4644126 0.85 MAPT (0.59) MAPTKMT2AALDH1A1LMNAHTT
SCHEMBL4641422 0.83 MAPT (0.58) MAPTKMT2AALDH1A1LMNAHTT
SCHEMBL27619978 0.83 MAPT (0.53) MAPTKMT2AALDH1A1LMNAHTT
SCHEMBL4644456 0.83 CA12 (0.51) MAPTKMT2AALDH1A1LMNAHTT
SCHEMBL4642418 0.82 KMT2A (0.60) MAPTKMT2AALDH1A1LMNAHTT
SCHEMBL4646126 0.82 CYP4A11 (0.57) MAPTKMT2AALDH1A1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100519671-C Film-forming polymer and antifouling paint JOTUN AS (NO) 2009-07-29 CN disclosed
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
CN-1643085-A Film-forming polymer and antifouling paint JOTUN AS (NO) 2005-07-20 CN disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed