Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PAM | P19021 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MDM4 | O15151 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4643237 | 1.00 | TSHR (0.43) | TSHRADRB2ADRB1ADRB3HCAR2 | |
| SCHEMBL4644386 | 0.90 | MAPT (0.49) | TSHRADRB2ADRB1ADRB3HCAR2 | |
| SCHEMBL4647772 | 0.90 | MAPT (0.49) | TSHRADRB2ADRB1ADRB3HCAR2 | |
| SCHEMBL6553849 | 0.87 | TSHR (0.41) | TSHRADRB2ADRB1ADRB3HCAR2 | |
| SCHEMBL4647774 | 0.82 | MAPT (0.49) | TSHRHCAR2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL4645084 | 0.82 | MAPT (0.49) | TSHRHCAR2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL4645073 | 0.82 | MAPT (0.49) | TSHRHCAR2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL4645106 | 0.82 | TSHR (0.50) | TSHRADRB2ADRB1ADRB3HCAR2 | |
| SCHEMBL4648058 | 0.82 | TSHR (0.50) | TSHRADRB2ADRB1ADRB3HCAR2 | |
| SCHEMBL4644624 | 0.81 | TSHR (0.38) | TSHRADRB2ADRB1ADRB3HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487928-B1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | JOTUN AS (NO) | 2008-08-13 | — | — | EP | disclosed |
| EP-1487928-A1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | Jotun AS (NO) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003080747-A1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | JOTUN AS (NO) | 2003-10-02 | — | — | WO | disclosed |