Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.59 |
| ▸ | KLKB1 | P03952 | 6/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3577876 | 0.89 | F10 (0.58) | F10KLKB1POLB | |
| SCHEMBL3582353 | 0.88 | POLB (0.55) | F10KLKB1POLB | |
| SCHEMBL3587146 | 0.86 | F10 (0.58) | F10KLKB1POLB | |
| SCHEMBL3830271 | 0.83 | F10 (0.63) | F10KLKB1POLB | |
| SCHEMBL3582471 | 0.82 | F10 (0.49) | F10KLKB1POLB | |
| SCHEMBL3584850 | 0.81 | POLB (0.52) | F10KLKB1POLB | |
| SCHEMBL3577875 | 0.79 | F10 (0.57) | F10KLKB1POLB | |
| SCHEMBL3581950 | 0.79 | POLB (0.57) | F10KLKB1POLB | |
| SCHEMBL20584247 | 0.79 | F10 (0.66) | F10KLKB1POLB | |
| SCHEMBL29581142 | 0.79 | F10 (0.66) | F10KLKB1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697318-B1 | PROLINYLARYLACETAMIDES | MERCK PATENT GMBH (DE) | 2008-08-27 | — | — | EP | claimed |