SCHEMBL4645657

SCHEMBL4645657

COC(=O)/C=C/C(=O)OCCCCC(=O)O[Si](C(C)C)(C(C)C)C(C)C

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.41
HCAR2 Q8TDS4 6/20 0.40
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37
MAPT P10636 1/20 0.36
RAB9A P51151 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ALDH1A1 P00352 3/20 0.34
LMNA P02545 2/20 0.34
IARS1 P41252 3/20 0.33
TSHR P16473 2/20 0.32
CYP3A4 P08684 1/20 0.32
KDM4E B2RXH2 1/20 0.32
GFPT1 Q06210 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4645264 1.00 ATM (0.41) ATMHCAR2KEAP1NFE2L2MAPT
SCHEMBL4645249 1.00 ATM (0.41) ATMHCAR2KEAP1NFE2L2MAPT
SCHEMBL4641502 0.96 ATM (0.42) ATMHCAR2KEAP1NFE2L2MAPT
SCHEMBL4641496 0.96 ATM (0.42) ATMHCAR2KEAP1NFE2L2MAPT
SCHEMBL4642481 0.96 ATM (0.42) ATMHCAR2KEAP1NFE2L2MAPT
SCHEMBL4642006 0.90 HCAR2 (0.41) ATMHCAR2KEAP1NFE2L2MAPT
SCHEMBL4643880 0.90 HCAR2 (0.41) ATMHCAR2KEAP1NFE2L2MAPT
SCHEMBL4641998 0.90 HCAR2 (0.41) ATMHCAR2KEAP1NFE2L2MAPT
SCHEMBL4644235 0.85 ATM (0.46) ATMHCAR2KEAP1NFE2L2MAPT
SCHEMBL4644225 0.85 ATM (0.46) ATMHCAR2KEAP1NFE2L2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed