Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9956486 | 0.77 | GRIK1 (0.40) | ALDH1A1TSHR | |
| SCHEMBL22092216 | 0.69 | — | — | |
| SCHEMBL5116954 | 0.67 | NPSR1 (0.50) | ALDH1A1 | |
| SCHEMBL5892080 | 0.65 | — | — | |
| SCHEMBL7101186 | 0.64 | GRIK1 (0.36) | TSHR | |
| SCHEMBL27750009 | 0.63 | — | — | |
| SCHEMBL22811 | 0.63 | GRIK1 (0.39) | ALDH1A1TSHRAKR1C3 | |
| SCHEMBL27166 | 0.63 | GRIK1 (0.39) | ALDH1A1TSHRAKR1C3 | |
| SCHEMBL6571066 | 0.63 | PTGS1 (0.36) | ALDH1A1TSHRAKR1C3 | |
| SCHEMBL6571057 | 0.63 | PTGS1 (0.36) | ALDH1A1TSHRAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1748043-B1 | Polysubstituted 1,1-pyridinyloxycyclopropanamine derivatives, process for their préparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2008-08-20 | — | — | EP | disclosed |
| EP-1748043-A1 | Polysubstituted 1,1-pyridinyloxycyclopropanamine derivatives, process for their préparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2007-01-31 | — | — | EP | disclosed |