SCHEMBL4645992

SCHEMBL4645992

CCCC(=O)c1ccccc1NCCOc1ccc(CC(Nc2ccccc2C(=O)c2ccccc2)C(=O)OC)cc1

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.59
PPARA Q07869 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4646653 0.97 PPARG (0.59) PPARGPPARA
SCHEMBL4647981 0.95 PPARG (0.59) PPARGPPARA
SCHEMBL4645679 0.94 PPARG (0.58) PPARGPPARA
SCHEMBL4647190 0.93 PPARG (0.57) PPARGPPARA
SCHEMBL4647592 0.93 PPARG (0.59) PPARGPPARA
SCHEMBL4648235 0.93 PPARG (0.67) PPARGPPARA
SCHEMBL4645108 0.93 PPARG (0.58) PPARGPPARA
SCHEMBL4645966 0.92 PPARG (0.57) PPARGPPARA
SCHEMBL4643264 0.92 PPARG (0.57) PPARGPPARA
SCHEMBL4645190 0.92 PPARG (0.57) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1778624-B1 TYROSINE DERIVATIVES AS PPAR-GAMMA-MODULATORS SALVAT LAB SA (ES) 2008-08-20 EP disclosed