⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL27963873 | 0.82 | — | — | |
| Methane SCHEMBL9978625 | 0.82 | — | — | |
| Methane SCHEMBL28142428 | 0.82 | — | — | |
| Methane SCHEMBL28156122 | 0.82 | — | — | |
| Methane SCHEMBL2977 | 0.82 | — | — | |
| Methane SCHEMBL28884810 | 0.67 | — | — | |
| Methane SCHEMBL2579966 | 0.67 | — | — | |
| Methane SCHEMBL28374425 | 0.67 | — | — | |
| Methane SCHEMBL29374620 | 0.67 | — | — | |
| Methane SCHEMBL28462159 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1298130-B1 | 3-HYDROXYMETHYLBENZO B THIOPHENE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | TEIJIN PHARMA LTD (JP) | 2008-08-13 | — | — | EP | claimed |
| EP-1298130-B1 | 3-HYDROXYMETHYLBENZO B THIOPHENE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | TEIJIN PHARMA LTD (JP) | 2008-08-13 | — | — | EP | disclosed |
| CN-1205204-C | 3-hydroxymethylbenzo [b] thiphene derivatives and process for their preparation | TEIJIN LTD (JP) | 2005-06-08 | — | — | CN | disclosed |
| US-6774245-B2 | SELECTIVE HYDROGENATION OF 7-SUBSTITUTED-3-HYDROXYMETHYL-BENZO(B)THIOPHENE DERIVATIVE; CYCLIZATION, SULFIDING | TEIJIN LIMITED (JP) | 2004-08-10 | — | — | US | disclosed |
| CN-1462271-A | 3-hydroxymethylbenzo [b] thiphene derivatives and process for their preparation | TEIJIN LTD (JP) | 2003-12-17 | — | — | CN | disclosed |
| US-20030191325-A1 | 3-Hydroxymethylbenzo[b]thiophene derivatives and process for their preparation | TEIJIN LIMITED (JP) | 2003-10-09 | — | — | US | disclosed |
| EP-1298130-A1 | 3-HYDROXYMETHYLBENZO B THIOPHENE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | TEIJIN LIMITED (JP) | 2003-04-02 | — | — | EP | disclosed |