Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA4 | P22748 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4646556 | 0.98 | PPARG (0.55) | PPARGCA12CA1CA2CA4 | |
| SCHEMBL4646461 | 0.94 | PPARG (0.63) | PPARGPPARA | |
| SCHEMBL4648061 | 0.92 | PPARG (0.60) | PPARGPPARA | |
| SCHEMBL4648525 | 0.92 | PPARG (0.59) | PPARGCA12CA1CA2CA4 | |
| SCHEMBL4644700 | 0.92 | PPARG (0.61) | PPARGPPARA | |
| SCHEMBL4643200 | 0.92 | PPARG (0.64) | PPARGPPARA | |
| SCHEMBL4643447 | 0.90 | PPARG (0.60) | PPARGPPARA | |
| SCHEMBL4643067 | 0.89 | PPARG (0.62) | PPARGPPARA | |
| SCHEMBL4648483 | 0.88 | PPARG (0.57) | PPARGPPARA | |
| SCHEMBL4646851 | 0.87 | PPARG (0.57) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778624-B1 | TYROSINE DERIVATIVES AS PPAR-GAMMA-MODULATORS | SALVAT LAB SA (ES) | 2008-08-20 | — | — | EP | disclosed |