SCHEMBL4646473

SCHEMBL4646473

c1cc(C2CS2)cc(C2CS2)c1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 4/20 0.33
HDAC4 P56524 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
KMO O15229 1/20 0.31
KDM1A O60341 2/20 0.31
SLC18A3 Q16572 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28529394 0.80
SCHEMBL383636 0.80
SCHEMBL27871634 0.78 TSHR (0.40) HTR2CKDM1ASLC18A3SIGMAR1
SCHEMBL11495069 0.72 TSHR (0.36) HTR2CKDM1AMAPT
SCHEMBL14675631 0.70
SCHEMBL6935362 0.67 HTR2C (0.52) HTR2CHDAC4HDAC2HDAC8KMO
SCHEMBL19036408 0.67 KDM1A (0.48) KDM1A
SCHEMBL5181880 0.66 SLC18A3 (0.42) SLC18A3SIGMAR1GAA
SCHEMBL5112225 0.65 IDO1 (0.33)
SCHEMBL28379460 0.65 ESR2 (0.43) KDM1AGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6201061-B1 CURING A RESIN FOR OPTICAL USE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2001-03-13 US claimed
US-20080206668-A1 NEGATIVE RESIST COMPOSITION AND PATTERN FORMING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2008-08-28 US disclosed
EP-1962139-A1 Negative resist composition and pattern forming method using the same FUJIFILM Corporation (JP) 2008-08-27 EP disclosed
EP-1120667-B1 Process for production of optical material MITSUBISHI GAS CHEMICAL CO (JP) 2005-06-22 EP disclosed
EP-1099721-B1 Composition for producing resin MITSUBISHI GAS CHEMICAL CO (JP) 2005-01-12 EP disclosed
US-6472495-B1 RESIN PRODUCED BY CURING THE COMPOSITION BY POLYMERIZATION HAS AN EXCELLENT IMPACT RESISTANCE AND OPTICAL PROPERTIES, AND IS SUITABLE AS AN OPTICAL MATERIAL. POLYMERS WITH SULFIDE, SELINIUM AND TELLURIUM MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2002-10-29 US disclosed
US-6444146-B2 DISCOLORATION INHIBITION MITSUBISHI GAS CHEMICAL CO. (JP) 2002-09-03 US disclosed
EP-1120667-A2 Process for production of optical material MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2001-08-01 EP disclosed
US-20010008278-A1 Process for production of optical material MITSUBISHI GAS CHEMICAL COMPANY, INC (JP) 2001-07-19 US disclosed
EP-1099721-A1 Composition for producing resin MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2001-05-16 EP disclosed