Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4641781 | 1.00 | HCAR2 (0.38) | HCAR2KEAP1NFE2L2TP53THRB | |
| SCHEMBL4645230 | 0.86 | HCAR2 (0.40) | HCAR2THRBALDH1A1NPSR1 | |
| SCHEMBL4646033 | 0.86 | HCAR2 (0.40) | HCAR2THRBALDH1A1NPSR1 | |
| SCHEMBL4641794 | 0.77 | HCAR2 (0.36) | HCAR2KEAP1NFE2L2 | |
| SCHEMBL7041364 | 0.73 | EPHX2 (0.35) | HCAR2TP53SLC6A3ALDH1A1NPSR1 | |
| SCHEMBL4645189 | 0.71 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL4641592 | 0.71 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL7041362 | 0.70 | HCAR2 (0.41) | HCAR2TP53SLC6A3NPSR1 | |
| SCHEMBL4641605 | 0.69 | HCAR2 (0.43) | HCAR2KEAP1NFE2L2TP53ALDH1A1 | |
| SCHEMBL4642281 | 0.69 | HCAR2 (0.43) | HCAR2KEAP1NFE2L2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487928-B1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | JOTUN AS (NO) | 2008-08-13 | — | — | EP | disclosed |
| EP-1487928-A1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | Jotun AS (NO) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003080747-A1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | JOTUN AS (NO) | 2003-10-02 | — | — | WO | disclosed |