SCHEMBL464778

SCHEMBL464778

CSCC[C@H](N)C(=O)OC(=O)[C@@H](N)Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALPI P09923 1/20 0.50
PKM P14618 1/20 0.50
PTGS1 P23219 1/20 0.50
XIAP P98170 1/20 0.50
SLC7A5 Q01650 1/20 0.50
KMT2A Q03164 1/20 0.46
ANPEP P15144 2/20 0.46
MME P08473 1/20 0.46
SLC15A1 P46059 1/20 0.44
RNPEP Q9H4A4 1/20 0.43
DNPEP Q9ULA0 1/20 0.43
FNTA P49354 3/20 0.43
FNTB P49356 3/20 0.43
PGGT1B P53609 3/20 0.43
LTA4H P09960 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL9051836 0.90 SLC7A5 (0.56) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL5159598 0.87 SLC7A5 (0.50) SLC7A5
SCHEMBL14658220 0.87 ALPI (0.45) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL28820471 0.84 SLC7A5 (0.68) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL288607 0.84 SLC7A5 (0.68) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL8835936 0.84 SLC7A5 (0.68) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL3495948 0.84 ALPI (0.44) ALPIPKMPTGS1XIAPSLC7A5
Dl-Phenylalanine SCHEMBL464776 0.84 SLC7A5 (0.69) ALPIPKMPTGS1XIAPSLC7A5
Dl-Phenylalanine SCHEMBL29503517 0.84 SLC7A5 (0.69) ALPIPKMPTGS1XIAPSLC7A5
Phenylalanine SCHEMBL28231547 0.84 SLC7A5 (0.69) ALPIPKMPTGS1XIAPSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3277098-A1 NOVEL AND USEFUL EDIBLE SALT AND METHODS OF USE AND PRODUCTION THEREOF E.k.salt Ltd. (IL) 2018-02-07 EP claimed
WO-2016157178-A1 NOVEL AND USEFUL EDIBLE SALT AND METHODS OF USE AND PRODUCTION THEREOF E.K.SALT LTD. (IL) 2016-10-06 WO claimed
US-9181224-B2 Bifunctional molecules with antibody-recruiting and entry inhibitory activity against the human immunodeficiency virus YALE UNIVERSITY (US) 2015-11-10 US claimed
WO-2006031844-A2 TREATING THE CAUSE OF BACK PAIN WITH TRACTION WITHIN HYPERBARIC CHAMBER YEUNG JEFFREY E (US) 2006-03-23 WO claimed
EP-1383793-A2 INSULIN AND IGF-1 RECEPTOR AGONISTS AND ANTAGONISTS DGI BioTechnologies, L.L.C. (US) 2004-01-28 EP claimed
WO-2001072771-A2 INSULIN AND IGF-1 RECEPTOR AGONISTS AND ANTAGONISTS DGI BIOTECHNOLOGIES, L.L.C. (US) 2001-10-04 WO claimed
US-5304658-A Quinone derivatives, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-04-19 US claimed
CN-115389756-B Detection kit for predicting risk of atrial fibrillation and application thereof 首都医科大学附属北京安贞医院 2023-02-17 CN disclosed
CN-115389756-A Detection kit for predicting risk of atrial fibrillation and application thereof 首都医科大学附属北京安贞医院 2022-11-25 CN disclosed
US-11366100-B2 P13K-MTORC1-S6K1 signaling pathway biomarkers predictive of anti-cancer responses DANA-FARBER CANCER INSTITUTE, INC. (US) 2022-06-21 US disclosed
US-20220145396-A1 METHOD OF IDENTIFYING PATIENTS WITH BORTEZOMIB RESISTANT MULTIPLE MYELOMA AND OTHER BLOOD DISEASES MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2022-05-12 US disclosed
US-20220135622-A1 ANTIBACTERIAL PEPTIDES AND METHODS OF USE GENENTECH, INC. (US) 2022-05-05 US disclosed
EP-3931205-A1 ANTIBACTERIAL PEPTIDES AND METHODS OF USE Genentech, Inc. (US) 2022-01-05 EP disclosed
WO-2003063909-A1 RESPONSIVE MICROGEL AND METHODS RELATED THERETO SUPRATEK PHARMA INC. (US) 2003-08-07 WO disclosed
CN-1339298-A Compound traditional medicine with piperine for increasing biological utilization of paeoniflorin and its preparing method TANG XIAOHAI (CN) 2002-03-13 CN disclosed
US-6074848-A AMINO ACID SEQUENCE; FOR ANTIPROLIFERATIVE AND WOUND HEALING AGENTS CHIRON CORPORATION (US) 2000-06-13 US disclosed
EP-0763107-A1 PANTROPIC NEUROTROPHIC FACTORS GENENTECH, INC. (US) 1997-03-19 EP disclosed
WO-1995033829-A1 PANTROPIC NEUROTROPHIC FACTORS GENENTECH, INC. (US) 1995-12-14 WO disclosed
EP-0331404-A2 Method for producing tropane alkaloid SEITAIKINOU RIYOU KAGAKUHIN SHINSEIZOUGIJUTSU KENKYU KUMIAI (JP) 1989-09-06 EP disclosed
US-4604286-A Infusion solution for parenteral nutrition DAIGO NUTRITIVE CHEMICALS, LTD. (JP) 1986-08-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220145396-A1 METHOD OF IDENTIFYING PATIENTS WITH BORTEZOMIB RESISTANT MULTIPLE MYELOMA AND OTHER BLOOD DISEASES PSMB5, PSMB4, PSMD5 ALPI 4250/4885PKM 3809/4885PTGS1 4188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.