SCHEMBL4647852

SCHEMBL4647852

CCOC(=O)/C=C\C(=O)OCC(=O)OC(=O)C(c1ccccc1)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.60
LMNA P02545 4/20 0.60
MDM2 Q00987 2/20 0.60
MDM4 O15151 1/20 0.60
L3MBTL1 Q9Y468 2/20 0.44
TSHR P16473 1/20 0.44
HCAR2 Q8TDS4 1/20 0.44
ALDH1A1 P00352 4/20 0.43
THRB P10828 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
CHRM1 P11229 3/20 0.42
CHRM3 P20309 3/20 0.42
CHRM2 P08172 2/20 0.42
CHRM4 P08173 2/20 0.42
CYP3A4 P08684 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4641786 1.00 MAPT (0.60) MAPTLMNAMDM2MDM4L3MBTL1
SCHEMBL4641776 1.00 MAPT (0.60) MAPTLMNAMDM2MDM4L3MBTL1
SCHEMBL4647092 0.89 MAPT (0.50) MAPTLMNAMDM2MDM4L3MBTL1
SCHEMBL4644152 0.89 MAPT (0.50) MAPTLMNAMDM2MDM4L3MBTL1
SCHEMBL4644145 0.89 MAPT (0.50) MAPTLMNAMDM2MDM4L3MBTL1
SCHEMBL4647776 0.86 MAPT (0.51) MAPTLMNAMDM2MDM4L3MBTL1
SCHEMBL4644387 0.86 MAPT (0.51) MAPTLMNAMDM2MDM4L3MBTL1
SCHEMBL4644393 0.86 MAPT (0.51) MAPTLMNAMDM2MDM4L3MBTL1
SCHEMBL4647902 0.84 MAPT (0.49) MAPTLMNAMDM2MDM4L3MBTL1
SCHEMBL4643566 0.84 MAPT (0.49) MAPTLMNAMDM2MDM4L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed