Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4647931 | 1.00 | PTPRC (0.46) | PTPRCMAPTALDH1A1POLBNPC1 | |
| SCHEMBL8175789 | 0.83 | MEN1 (0.37) | MAPTALDH1A1LMNAKEAP1NFE2L2 | |
| SCHEMBL4648990 | 0.82 | IDO1 (0.43) | MAPTALDH1A1LMNAKEAP1NFE2L2 | |
| SCHEMBL4648986 | 0.82 | IDO1 (0.43) | MAPTALDH1A1LMNAKEAP1NFE2L2 | |
| SCHEMBL4787268 | 0.79 | PTPN1 (0.36) | MAPTALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL4787270 | 0.79 | PTPN1 (0.36) | MAPTALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL8170720 | 0.75 | CYP19A1 (0.37) | PTPRCMAPTALDH1A1NSD2LMNA | |
| SCHEMBL8173700 | 0.74 | FGFR1 (0.36) | PTPRCMAPTALDH1A1POLBNPC1 | |
| Naftazone SCHEMBL1697156 | 0.74 | MEN1 (0.44) | PTPRCMAPTALDH1A1POLBP2RX7 | |
| Naftazone SCHEMBL29615756 | 0.74 | MEN1 (0.44) | PTPRCMAPTALDH1A1POLBP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1961738-A1 | New compounds with antiglutamatergic properties and uses thereof | Faust Pharmaceuticals (FR) | 2008-08-27 | — | — | EP | disclosed |