Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3576970 | 0.91 | F10 (0.61) | F10POLBKLKB1MAPTL3MBTL1 | |
| SCHEMBL3577935 | 0.86 | F10 (0.51) | F10POLBKLKB1MAPTMEN1 | |
| SCHEMBL3580419 | 0.86 | F10 (0.56) | F10POLBKLKB1MAPTALOX5 | |
| SCHEMBL3591639 | 0.86 | F10 (0.56) | F10POLBKLKB1MAPTALOX5 | |
| SCHEMBL3593333 | 0.85 | F10 (0.47) | F10POLBKLKB1MAPTALOX5 | |
| SCHEMBL3581950 | 0.85 | POLB (0.57) | F10POLBKLKB1MAPTALOX5 | |
| SCHEMBL4647614 | 0.84 | KLKB1 (0.55) | F10POLBKLKB1MAPTALOX5 | |
| SCHEMBL3582353 | 0.83 | POLB (0.55) | F10POLBKLKB1MAPTMEN1 | |
| SCHEMBL3581006 | 0.83 | F10 (0.52) | F10POLBKLKB1MAPTCCR1 | |
| SCHEMBL3594321 | 0.83 | F10 (0.51) | F10POLBKLKB1MAPTALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697318-B1 | PROLINYLARYLACETAMIDES | MERCK PATENT GMBH (DE) | 2008-08-27 | — | — | EP | claimed |