Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.69 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4643346 | 0.98 | PPARG (0.70) | PPARGPPARA | |
| SCHEMBL4646196 | 0.95 | PPARG (0.67) | PPARGPPARA | |
| SCHEMBL4646224 | 0.93 | PPARG (0.80) | PPARGPPARA | |
| SCHEMBL4648057 | 0.93 | PPARG (0.65) | PPARGPPARA | |
| SCHEMBL4648481 | 0.92 | PPARG (0.62) | PPARGPPARA | |
| SCHEMBL4646339 | 0.92 | PPARG (0.57) | PPARGPPARA | |
| SCHEMBL4643333 | 0.91 | PPARG (0.81) | PPARGPPARA | |
| SCHEMBL4643444 | 0.90 | PPARG (0.64) | PPARGPPARA | |
| SCHEMBL4645366 | 0.90 | PPARG (0.64) | PPARGPPARA | |
| SCHEMBL4642779 | 0.90 | PPARG (0.61) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778624-B1 | TYROSINE DERIVATIVES AS PPAR-GAMMA-MODULATORS | SALVAT LAB SA (ES) | 2008-08-20 | — | — | EP | disclosed |