SCHEMBL4648901

SCHEMBL4648901

O=P(O)(O)C(CC=NOCc1ccccc1)c1ccc(Cl)c(Cl)c1

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
SLC6A3 Q01959 1/20 0.41
MEN1 O00255 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
KMT2A Q03164 1/20 0.39
ACP3 P15309 1/20 0.38
PTPN5 P54829 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4648899 1.00 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3MEN1CYP2D6
SCHEMBL4689914 0.87 ACP3 (0.43) SLC6A2SLC6A4SLC6A3MEN1KMT2A
SCHEMBL4689913 0.87 ACP3 (0.43) SLC6A2SLC6A4SLC6A3MEN1KMT2A
SCHEMBL4425880 0.85 ACP3 (0.53) MEN1KMT2AACP3
SCHEMBL4425878 0.85 ACP3 (0.53) MEN1KMT2AACP3
SCHEMBL4426586 0.85 MAPT (0.42) SLC6A2SLC6A4SLC6A3MEN1CYP2D6
SCHEMBL4426588 0.85 MAPT (0.42) SLC6A2SLC6A4SLC6A3MEN1CYP2D6
SCHEMBL4426515 0.82 ACP3 (0.43) ACP3
SCHEMBL4426520 0.82 ACP3 (0.43) ACP3
SCHEMBL4649855 0.81 ACP3 (0.49) ACP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1963344-A1 ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS UNIVERSITEIT GENT (BE) 2008-09-03 EP disclosed
WO-2007071453-A1 ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS UNIVERSITEIT GENT (BE) 2007-06-28 WO disclosed