Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2896975 | 0.86 | PTPN1 (0.50) | PTPN1PTPN2 | |
| SCHEMBL2888708 | 0.84 | PTPN1 (0.50) | PTPN1PTPN2 | |
| SCHEMBL2894970 | 0.84 | PTPN1 (0.50) | PTPN1PTPN2 | |
| SCHEMBL2894829 | 0.84 | PTPN1 (0.52) | PTPN1PTPN2 | |
| Potassium SCHEMBL2896581 | 0.83 | PTPN1 (0.49) | PTPN1PTPN2 | |
| SCHEMBL2896579 | 0.83 | PTPN1 (0.49) | PTPN1PTPN2 | |
| SCHEMBL4785652 | 0.80 | PTPN1 (0.56) | PTPN1PTPN2 | |
| SCHEMBL2895668 | 0.78 | PTPN1 (0.54) | PTPN1PTPN2 | |
| SCHEMBL2895946 | 0.77 | PTPN1 (0.61) | PTPN1PTPN2 | |
| SCHEMBL2897340 | 0.76 | PTPN1 (0.52) | PTPN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963293-A1 | 1-ORTHOFLUOROPHENYL SUBSTITUTED 1, 2 , 5-THIAZOLIDINEDIONE DERIVATIVES AS PTP-AS INHIBITORS | Novartis AG (CH) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007067612-A1 | 1-ORTHOFLUOROPHENYL SUBSTITUTED 1, 2, 5-THIAZOLIDINEDIONE DERIVATIVES AS PTP-AS INHIBITORS | NOVARTIS AG (CH) | 2007-06-14 | — | — | WO | disclosed |