SCHEMBL4649374

SCHEMBL4649374

[CH2]C(C)(C)CBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL93926 0.78
SCHEMBL11419097 0.78
SCHEMBL4649559 0.78
SCHEMBL809367 0.76
SCHEMBL1941673 0.72
SCHEMBL626928 0.70
SCHEMBL83728 0.67
SCHEMBL1398293 0.67
SCHEMBL6909627 0.67
SCHEMBL83309 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102492175-B Microcapsule flame-retardant adsorption resin and preparation method thereof, and flame-retardant composite material USTC UNIV SCIENCE TECH CN 2013-05-29 CN claimed
CN-102492175-A Microcapsule flame-retardant adsorption resin and preparation method thereof, and flame-retardant composite material USTC UNIV SCIENCE TECH CN 2012-06-13 CN claimed
EP-1824824-A1 INTERMEDIATES FOR THE PREPARATION OF LERCANIDIPINE Motivan Ltd. (IL) 2007-08-29 EP claimed
WO-2006059332-A1 INTERMEDIATES FOR THE PREPARATION OF LERCANIDIPINE MOTIVAN LTD. (IL) 2006-06-08 WO claimed
CN-110003209-A Macrocyclic compound as TRK kinase inhibitor 阵列生物制药公司 2019-07-12 CN disclosed
CN-105693720-B Macrocyclic compound as TRK kinase inhibitor 阵列生物制药公司 2019-01-18 CN disclosed
CN-105693720-A Macrocyclic compounds as TRK kinase inhibitors 阵列生物制药公司 2016-06-22 CN disclosed
CN-102492175-B Microcapsule flame-retardant adsorption resin and preparation method thereof, and flame-retardant composite material USTC UNIV SCIENCE TECH CN 2013-05-29 CN disclosed
CN-102971291-A Novel amide derivative and use thereof as medicine MITSUBISHI TANABE PHARMA CORP 2013-03-13 CN disclosed
CN-102492175-A Microcapsule flame-retardant adsorption resin and preparation method thereof, and flame-retardant composite material USTC UNIV SCIENCE TECH CN 2012-06-13 CN disclosed
EP-1851233-B1 METHOD FOR PRODUCING TERTIARY PHOSPHINES BASF SE (DE) 2008-09-03 EP disclosed
US-20080146850-A1 Method for Producing Tertiary Phosphines BASF AKTIENGESELLSCHAFT (DE) 2008-06-19 US disclosed
WO-1997028112-A1 DIHALOPROPENE COMPOUNDS, THEIR USE AS INSECTICIDES/ACARICIDES AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-08-07 WO disclosed
EP-0787710-A1 Fluoropropene compound, an insecticide containing the same and an intermediate for production thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-08-06 EP disclosed
WO-1996033160-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-10-24 WO disclosed
EP-0722430-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-07-24 EP disclosed
WO-1996004228-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-02-15 WO disclosed
US-4885381-A Phosphate-phosphites acid halides THE DOW CHEMICAL COMPANY (US) 1989-12-05 US disclosed
US-4755547-A Halogenated phosphate-phosphites and their acid halides and acids THE DOW CHEMICAL COMPANY (US) 1988-07-05 US disclosed
US-3957923-A FIREPROOFING E. I. DU PONT DE NEMOURS & COMPANY (US) 1976-05-18 US disclosed