Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CDC25B | P30305 | 2/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GGT1 | P19440 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28260571 | 0.93 | HTT (0.62) | HTTAKR1C3ALDH1A1ALOX15KMT2A | |
| SCHEMBL3694635 | 0.92 | AKR1C3 (0.59) | HTTCDC25BELANEAKR1C3ALDH1A1 | |
| SCHEMBL6003587 | 0.91 | HTT (0.59) | HTTAKR1C3ALDH1A1ALOX15KMT2A | |
| SCHEMBL143861 | 0.91 | HTT (0.53) | HTTAKR1C3ALDH1A1ALOX15KMT2A | |
| SCHEMBL29395127 | 0.91 | HTT (0.53) | HTTAKR1C3ALDH1A1ALOX15KMT2A | |
| Water SCHEMBL7618236 | 0.89 | HTT (0.52) | HTTAKR1C3ALDH1A1ALOX15KMT2A | |
| SCHEMBL10699806 | 0.86 | HTT (0.50) | HTTAKR1C3ALDH1A1ALOX15KMT2A | |
| Butane SCHEMBL15005123 | 0.86 | HTT (0.54) | HTTALDH1A1KMT2AKDM4EHPGD | |
| SCHEMBL11066360 | 0.84 | CTNNB1 (0.54) | HTTAKR1C3ALDH1A1ALOX15KMT2A | |
| SCHEMBL29435067 | 0.84 | CTNNB1 (0.58) | HTTAKR1C3ALDH1A1ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963433-A2 | ANNULAR OR TUBULAR SHAPED ARTICLES OF NOVEL POLYMER BLENDS | General Electric Company (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007075365-A2 | ANNULAR OR TUBULAR SHAPED ARTICLES OF NOVEL POLYMER BLENDS | GENERAL ELECTRIC COMPANY (US) | 2007-07-05 | — | — | WO | disclosed |
| EP-0594386-B1 | Ductile blends of polyester-carbonate and polyimide resins | GEN ELECTRIC (US) | 2003-09-17 | — | — | EP | disclosed |
| EP-0325718-A2 | Ternary polymer blends containing a polyetherimide, a polyphthalate carbonate, and rubber modified vinyl aromatic polymer | GENERAL ELECTRIC COMPANY (US) | 1989-08-02 | — | — | EP | disclosed |
| US-4612400-A | Autoxidation of bis(ortho dialkyl-phenoxy)benzophenones | THE DOW CHEMICAL COMPANY (US) | 1986-09-16 | — | — | US | disclosed |
| EP-0181000-A2 | Foamable polyetherimide resin formulation | GENERAL ELECTRIC COMPANY (US) | 1986-05-14 | — | — | EP | disclosed |
| US-4577034-A | Autoxidation of bis(ortho dialkyl-phenoxy)benzophenones | THE DOW CHEMICAL COMPANY (US) | 1986-03-18 | — | — | US | disclosed |
| EP-0158734-A1 | Thermally stabilized polyetherimides | GENERAL ELECTRIC COMPANY (US) | 1985-10-23 | — | — | EP | disclosed |
| US-4543368-A | DIHYDRODIAZINONE BLOWING AGENT | GENERAL ELECTRIC COMPANY (US) | 1985-09-24 | — | — | US | disclosed |
| US-4508861-A | CONTAINING ANTIOXIDANT SELECTED FROM HINDERED PHENOLS, ARYL PHOSPHONITES, ORGANIC PHOSPHITES, THIOESTERS OR MIXTURES | GENERAL ELECTRIC COMPANY (US) | 1985-04-02 | — | — | US | disclosed |